By Victor Parsons

ISBN-10: 0723407355

ISBN-13: 9780723407355

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Extra resources for A Colour Atlas of Bone Disease (Wolfe Medical Atlases)

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The incidence among patients o~ primary hyperparathyroidism with renal stones is in the order of 5 per cent. however, bone disease is rare in patients with calculi. ;. -~Hyperparathyrmihsm - renal '7 calculi 174 Parathyroid tissue . hyperplasia 55 Excessive mobilisation of calcium from the bones occurs in both primary and secondary hyperparathyroidism and results in metastatic calcification, especially in the walls of arterioles, as in this section of cerebrum (176 H&E x 120). Hyperparathyroidism is the most common cause of nephrocalcinosis which is visible radiologically in about 15 per cent of cases (177).

Osteomalacia Osteomalacia is the adult counterpart of rickets and is characterised by failure of mineralisation and an excess of osteoid due to interference with calcification mechanisms (see 77). The osteoid is increased at the expense of mineralised bone (117,118). The diagnosis is established by bone biopsy and the examination of a mineralised section ground and stained by von Kossa's method which stains the mineral black/brown and leaves the osteoid unstained (119 x 200). Alternatively Goldner's method may be used which stains the mineralised bone blue and the osteoid orange (120 x 360).

59 4. Tumours of bone Tumours of bone can be classified as benign or malignant and according to the bone tissues involved. a. Benign tumours of bone 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. Osteoma Osteoid osteoma Osteoblastoma Haemangioma Aneurysmal bone cyst Simple bone cyst (Reparative) granuloma of jaw Osteocartilaginous exostosis Chondroblastoma Chondromyxoid fibroma b. Malignant tumours of bone 1. Osteosarcoma 2. Parosteal osteosarcoma a. Benign tumours of bone 1. Osteoma Osteoma is a benign, slow growing neoplasm arising from the membranous bones of the face and skull (193).

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A Colour Atlas of Bone Disease (Wolfe Medical Atlases) by Victor Parsons

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